N-Acetyl Cysteine can improve immune health
2020.06.29
N-Acetyl Cysteine acts as an antioxidant in human body. It can improve immune function and contribute to improving respiratory and liver health.
N-Acetyl Cysteine is one of the derivatives of L-Cysteine, which is a sulfur containing proteinogenic amino acid. N-Acetyl Cysteine has an antioxidant function and is a precursor of Glutathione in the body. Thus, it is essential for immune health and prevention of cell damages.
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N-Acetyl Cysteine can control the release of cytokines and inhibit virus infection; consequently, it contributes to anti-inflammation and immune function. N-Acetyl Cysteine is known to prevent diseases such as pneumonia, hepatitis and osteoarthritis.
N-Acetyl Cysteine is widely used to control mucus hypersecretion, which can cause cough, sputum, and decline in lung function.
N-Acetyl Cysteine can boost immune response in the body. According to the studies, N-Acetyl Cysteine reduced the frequency and duration of influenza infection by controlling virus replication and expression of pro-inflammatory molecules with Influenza A. Furthermore, N-Acetyl Cysteine improves the functions of lymphocytes and neutrophils as well as the cytokine levels.
*Cytokines: Signaling molecules that mediate and regulate immunity, inflammation and hematopoiesis
*TNF: Tumor necrosis factor. A substance that causes inflammation or welling
*IL: Interleukins. A substance that regulates cell growth and immune responses, such as inflammation
References :
- Button at al (2018), Roles of mucus adhesion and cohesion in cough clearance, PNAS
- Flora et al.,(1997), Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment. The European Respiratory Journal
- Geiler J at al., (2010), N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus, Biochemical Pharmacology
- McCarty at al.(2020), Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus, Progress in Cardiovascular Diseases
- Palacio at al., (2011) Anti-inflammatory properties of N-acetylcysteine on lipopolysaccharide-activated macrophages, Inflammation Research
- Sadowska et al.,(2006), Role of N-acetylcysteine in the management of COPD, International Journal of Chronic Obstructive Pulmonary Disease
- Schmitt et al.,(2015), Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: A comparative crossover study, Redox Biology
- Zhang et al.,(2018), N-acetylcysteine improves oxidative stress and inflammatory response in patients with community acquired pneumonia, Medicine